Benefits of Hibiscus sabdariffa

Rich inRecommendable for

Malic acid;
Anthocyanins;
Ascorbic acid;
Minerals (Calcium and Iron);
Protocatechuic acid

High blood pressure
Liver disease
Antioxidant effect
Phase II Liver detox
Mild Diuretic
Inhibition of the angiotensin I-converting enzyme

Hibiscus decoctions and infusions of calyxes, and on occasion leaves, are used in at least 10 countries worldwide in the treatment of hypertension and hyperlipidemia with no reported adverse events or side effects. Mainly the flowers and leaves are used in ayurveda, india’s medicinal system, for treating ailments and health problems.

Here we review the phytochemical, pharmacological and toxicological properties of Hibiscus sabdariffa L. (English: roselle, red sorrel; Arabic: karkade), the calyces of which are used in many parts of the world to make cold and hot drinks. Nutritionally, these contain ascorbic acid (vitamin C). In folk medicine, the calyx extracts are used for the treatment of several complaints, including high blood pressure, liver diseases and fever. The pharmacological actions of the calyx extracts include strong in vitro and in vivo antioxidant activity. In rats and rabbits, the extract showed antihypercholesterolemic, antinociceptive and antipyretic, but not antiinflammatory activities. In rat and man a strong antihypertensive action has been demonstrated. Anthocyanins found in abundance in calyxes are generally considered the phytochemicals responsible for the antihypertensive and hypocholesterolemic effects, however evidence has also been provided for the role of polyphenols and hibiscus acid. There are also associated antioxidant effects of the anthocyanins inhibition of LDL-C oxidation which impedes atherosclerosis, an important cardiovascular risk factor.

Hibiscus sabdariffa anthocyanin extract can act as a prophylactic by intervening as a free radical scavenger both in vitro and in vivo as well as inducing the phase II drug detoxification enzymes.

The daily consumption of a tea or extract produced from calyxes significantly lowered systolic blood pressure (SBP) and diastolic blood pressure (DBP) in adults with pre to moderate essential hypertension and type 2 diabetes.
Hibiscus tea was as effective at lowering blood pressure as the commonly used blood pressure medication Captropril.

Total cholesterol, low-density lipoprotein cholesterol, and triglycerides were lowered in the majority of normolipidemic, hyperlipidemic, and diabetic animal models, whereas high-density lipoprotein cholesterol was generally not affected by the consumption of Hibiscus extract.

Extracts from Hibiscus have been shown to inhibit the growth of a variety of cancer cells. In particular, recent studies found that polyphenols extracted by organic solvents can inhibit melanoma cell growth.

Extracts from Hibiscus have been shown to inhibit the growth of a variety of cancer cells. In particular, recent studies found that polyphenols extracted from Hibiscus sabdariffa by organic solvents can inhibit melanoma cell growth.
These data are consistent with recent studies indicating that H. sabdariffa leaf extracts contain polyphenols that specifically inhibit the growth of melanoma cells, but not nontransformed cells.

On top of that this plant also acts as an apoptosis inducer in Human Gastric Cancer cells and these findings may open interesting perspectives to the strategy in human gastric cancer treatment. inhibited its growth by 50%

Hibiscus sabdariffa Leaf Extract Inhibits Human Prostate Cancer Cells.

Adverse effects

In healthy men, consumption of H. sabdariffa has resulted in significant decreases in the urinary concentrations of creatinine, uric acid, citrate, tartrate, calcium, sodium, potassium and phosphate.
The plant extracts are characterized by a very low degree of toxicity. There is no evidence of hepatic or renal toxicity as the result of HS extract consumption, except for possible adverse hepatic effects at high doses. A single report has suggested that excessive doses for relatively long periods could have a deleterious effect on the testes of rats.

H. rosa-sinensis may be harmful to healthy individuals and its use should be completely avoided in pregnancy.

References

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482446/

https://www.ncbi.nlm.nih.gov/pubmed/25694272

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198834

https://www.ncbi.nlm.nih.gov/pubmed/24549255

https://www.ncbi.nlm.nih.gov/pubmed/27618152

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516987/

https://www.ncbi.nlm.nih.gov/pubmed/15791651

https://www.ncbi.nlm.nih.gov/pubmed/16106391

https://www.ncbi.nlm.nih.gov/pubmed/23333908

https://www.ncbi.nlm.nih.gov/pubmed/21314460

https://www.ncbi.nlm.nih.gov/pubmed/16222626

https://www.ncbi.nlm.nih.gov/pubmed/25875025

https://www.ncbi.nlm.nih.gov/pubmed/21480802

https://www.ncbi.nlm.nih.gov/pubmed/19678781

https://www.ncbi.nlm.nih.gov/pubmed/19962289

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608971

https://www.ncbi.nlm.nih.gov/pubmed/17765418

https://www.ncbi.nlm.nih.gov/pubmed/23749748

https://www.ncbi.nlm.nih.gov/pubmed/25875025

https://www.ncbi.nlm.nih.gov/pubmed/24668839

https://www.ncbi.nlm.nih.gov/pubmed/20018807

Written by Igor Nelson

2 thoughts on “Benefits of Hibiscus sabdariffa

  • February 14, 2019 at 9:37 am
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