|Rich in||Recommendable for|
Minerals (Calcium and Iron);
High blood pressure
Phase II Liver detox
Inhibition of the angiotensin I-converting enzyme
Hibiscus decoctions and infusions of calyxes, and on occasion leaves, are used in at least 10 countries worldwide in the treatment of hypertension and hyperlipidemia with no reported adverse events or side effects. Mainly the flowers and leaves are used in ayurveda, india’s medicinal system, for treating ailments and health problems.
Here we review the phytochemical, pharmacological and toxicological properties of Hibiscus sabdariffa L. (English: roselle, red sorrel; Arabic: karkade), the calyces of which are used in many parts of the world to make cold and hot drinks. Nutritionally, these contain ascorbic acid (vitamin C). In folk medicine, the calyx extracts are used for the treatment of several complaints, including high blood pressure, liver diseases and fever. The pharmacological actions of the calyx extracts include strong in vitro and in vivo antioxidant activity. In rats and rabbits, the extract showed antihypercholesterolemic, antinociceptive and antipyretic, but not antiinflammatory activities. In rat and man a strong antihypertensive action has been demonstrated. Anthocyanins found in abundance in calyxes are generally considered the phytochemicals responsible for the antihypertensive and hypocholesterolemic effects, however evidence has also been provided for the role of polyphenols and hibiscus acid. There are also associated antioxidant effects of the anthocyanins inhibition of LDL-C oxidation which impedes atherosclerosis, an important cardiovascular risk factor.
Hibiscus sabdariffa anthocyanin extract can act as a prophylactic by intervening as a free radical scavenger both in vitro and in vivo as well as inducing the phase II drug detoxification enzymes.
The daily consumption of a tea or extract produced from calyxes significantly lowered systolic blood pressure (SBP) and diastolic blood pressure (DBP) in adults with pre to moderate essential hypertension and type 2 diabetes.
Hibiscus tea was as effective at lowering blood pressure as the commonly used blood pressure medication Captropril.
Total cholesterol, low-density lipoprotein cholesterol, and triglycerides were lowered in the majority of normolipidemic, hyperlipidemic, and diabetic animal models, whereas high-density lipoprotein cholesterol was generally not affected by the consumption of Hibiscus extract.
Extracts from Hibiscus have been shown to inhibit the growth of a variety of cancer cells. In particular, recent studies found that polyphenols extracted by organic solvents can inhibit melanoma cell growth.
Extracts from Hibiscus have been shown to inhibit the growth of a variety of cancer cells. In particular, recent studies found that polyphenols extracted from Hibiscus sabdariffa by organic solvents can inhibit melanoma cell growth.
These data are consistent with recent studies indicating that H. sabdariffa leaf extracts contain polyphenols that specifically inhibit the growth of melanoma cells, but not nontransformed cells.
On top of that this plant also acts as an apoptosis inducer in Human Gastric Cancer cells and these findings may open interesting perspectives to the strategy in human gastric cancer treatment. inhibited its growth by 50%
Hibiscus sabdariffa Leaf Extract Inhibits Human Prostate Cancer Cells.
In healthy men, consumption of H. sabdariffa has resulted in significant decreases in the urinary concentrations of creatinine, uric acid, citrate, tartrate, calcium, sodium, potassium and phosphate.
The plant extracts are characterized by a very low degree of toxicity. There is no evidence of hepatic or renal toxicity as the result of HS extract consumption, except for possible adverse hepatic effects at high doses. A single report has suggested that excessive doses for relatively long periods could have a deleterious effect on the testes of rats.
H. rosa-sinensis may be harmful to healthy individuals and its use should be completely avoided in pregnancy.
Written by Igor Nelson